ascorbic acid diminishes developmental damages induced by high glucose in mouse preimplantation emberyos in vitro

Ascorbic Acid Diminishes Developmental Damages Induced by High Glucose in Mouse Preimplantation Emberyos in vitro

The effect of ascorbic acid on the acquisition and expression of nicotine-induced CPP in mouse

Increased activity of mesolimbic dopaminergic system within ventral tegmental area (VTA) due to nicotine results in psychologic dependence. It has been argued that function of dopamine receptors could by affected by ascorbic acid (AA). Furthermore, AA can decrease the withdrawal syndrome signs in addicted animals and may postpone the development of nicotine dependence. In the present study, the...

Alleviation of ascorbic acid-induced gastric high acidity by calcium ascorbate in vitro and in vivo

Ascorbic acid is one of the most well-known nutritional supplement and antioxidant found in fruits and vegetables. Calcium ascorbate has been developed to mitigate the gastric irritation caused by the acidity of ascorbic acid. The aim of this study was to compare calcium ascorbate and ascorbic acid, focusing on their antioxidant activity and effects on gastric juice pH, total acid output, and p...

The effect of ascorbic acid on the acquisition and expression of nicotine-induced CPP in mouse

Increased activity of mesolimbic dopaminergic system within ventral tegmental area (VTA) due to nicotine results in psychologic dependence. It has been argued that function of dopamine receptors could by affected by ascorbic acid (AA). Furthermore, AA can decrease the withdrawal syndrome signs in addicted animals and may postpone the development of nicotine dependence. In the present study, the...

Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest.

Sirtuins are a phylogenetically conserved NAD+-dependent protein deacetylase/ADP-ribosyltransferase family implicated in diverse biological processes. Several family members localize to mitochondria, the function of which is thought to determine the developmental potential of preimplantation embryos. We have therefore characterized the role of sirtuins in mouse preimplantation development under...

P-25: Study of the Effect of Experimental Diabetes Induced by STZ on In vitro Fertilization and Preimplantation Embryo Development Rate in Male Mouse Model

Background: Diabetes is a metabolic disease caused by a deficiency in the pancreatic secretion of insulin and/or by the inability of tissues to efficiently respond to insulin, events that cause hyperglycemia and affect all organs.Tissue alterations caused by diabetes affect different organic systems , including the male reproductive system. Reproductive dysfunction is one of the common secondar...